Erica, Robin Tinghitella and Scott Taylor have a new review on the impacts of climate change on temperature sensitive reproductive barriers in insects. Check out the open-access article in Frotiners of Ecology and Evolution (here)
Our hybridizing Chrysochus beetles are featured on the cover of the Journal of Evolutionary Biology!
Our Chrysochus hybrid zone paper was accepted at the Journal of Evolutionary Biology. We provide a direct link between cryptic barriers studied in the lab over a range of heterospecific mating frequencies, and hybrid zone dynamics.
Our paper won the 2018 GENETICS Editors’ Choice Award for Population Genetics!
Erica L. Larson, Dan Vanderpool, Brice A. J. Sarver, Colin Callahan, Sara Keeble, Lorraine L. Provencio, Michael D. Kessler, Vanessa Stewart, Erin Nordquist, Matthew D. Dean, and Jeffrey M. Good
Genetics July 2018 209: 845–859
Reproductive barriers are often assumed to arise from fixed genetic differences between species, despite frequent individual variation in the strength of reproductive isolation between populations. Larson et al. report polymorphism at several hybrid male sterility loci in house mice, and their results demonstrate that selection against deleterious hybrid interactions can drive the introgression of hybrid incompatibilities, highlighting the need for more extensive sampling of natural variation in speciation studies.
Automated Nuclear Cartography Reveals Conserved Sperm Chromosome Territory Localization across 2 Million Years of Mouse Evolution
Spermatogenesis and the Evolution of Mammalian Sex Chromosomes
Erica L. Larson, Emily E.K. Kopania, and Jeffrey M. Good
Developmental constraint and sexual conflict shape the evolution of hetero- morphic sex chromosomes. These contrasting forces are perhaps strongest during spermatogenesis in species with XY males. In this review, we consider how the unique regulatory environment and selective pressures of spermato- genesis interact to impact sex chromosome evolution in mammals. We explore how each developmental phase of spermatogenesis influences sex chromo- some gene content, structure, and rate of molecular evolution, and how these attributes may contribute to speciation. We argue that a developmental context is fundamental to understanding sex chromosome evolution and that an evolutionary perspective can shed new light on our understanding of sperm development. PAPER
A collaboration with Peter Ellis' group to quantify sperm nuclear morphology in classic and wild mice. Preprint.
A high-throughput method for unbiased quantitation and categorisation of nuclear morphology
Benjamin Matthew Skinner, Claudia Cattoni Rathje, Joanne Bacon, Emma Elizabeth Philippa Johnson, Erica Lee Larson, Emily Emiko Konishi Kopania, Jeffrey Martin Good, Gullalaii Yousafzai, Nabeel Ahmed Affara, Peter James Ivor Ellis
Re-thinking incompatibilities as fixed between species
The Evolution Of Polymorphic Hybrid Incompatibilities In House Mice
Erica L. Larson, Dan Vanderpool, Brice A. J. Sarver, Colin Callahan, Sara Keeble, Lorraine P. Provencio, Michael D. Kessler, Vanessa Stewart, Erin Nordquist, Matthew D. Dean and Jeffrey M. Good
Our new paper presenting whole exomes of a set of mouse strains that harbor more variation than existing mouse resources, demonstrating these new data can improve our power to link genotype to phenotype in house mice.
Whole Exome Sequencing Of Wild-Derived Inbred Strains Of Mice Improves Power To Link Phenotype And Genotype
Peter L. Chang, Emily Kopania, Sara Keeble, Brice A. J. Sarver, Erica Larson, Annie Orth, Khalid Belkhir, Pierre Boursot, François Bonhomme, Jeffrey M. Good, Matthew D. Dean